Cyclobenzaprine Wikipedia
If you are prescribed cyclobenzaprine, follow your healthcare provider’s directions for how to take it. Muscle relaxants are a somewhat common prescription due to the frequency of acute and chronic back pain. Low back pain is a very common issue — it remains among the top five reasons people see a primary healthcare provider. Most cases of low back pain resolve without medical intervention.
- In three of these studies there was a significantly greater improvement with FLEXERIL than with diazepam, while in the other studies the improvement following both treatments was comparable.
- It is unknown if Flexeril passes into breast milk or if it could harm a nursing baby.
- Flexeril is the brand name for Cyclobenzaprine, a prescription muscle relaxer that is similar to a class of Antidepressant drugs called Tricyclic Antidepressants.
- Although Flexeril doesn’t produce a euphoric high like many other drugs, people still misuse it due to its relaxing effects; many will increase dosages to amplify those effects.
When people addicted to Flexeril attempt to stop taking it or reduce their doses they may start to experience withdrawal symptoms, although these are typically not severe. Flexeril withdrawal symptoms can include headache, nausea, fatigue, and cravings for the drug. The most common adverse reactions to cyclobenzaprine are somnolence, dry mucous membranes, dizziness, and confusion. Less commonly, tachycardia, dysarthria, disorientation, and hallucinations have been reported [2]. Cyclobenzaprine is a drug prescribed to treat pain and discomfort.
Interactions that can increase the effect of cyclobenzaprine
Elderly patients seem to tolerate cyclobenzaprine less and may develop hallucinations as well as significant anticholinergic side effects, such as sedation. The use of significant lower dosing schedules in elderly patients may be prudent. How cyclobenzaprine (Flexeril) works is not well understood, but it helps alleviate stiffness, pain, and discomfort due to sprains, strains, or injuries to muscles.
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Observation with cardiac monitoring and observation for signs of CNS or respiratory depression, hypotension, cardiac dysrhythmias and/or conduction blocks, and seizures is necessary. If signs of toxicity occur at any what are flexeril time during this period, extended monitoring is required. Monitoring of plasma drug levels should not guide management of the patient. Dialysis is probably of no value because of low plasma concentrations of the drug.
What should I do if I forget a dose?
Call your doctor or local poison control center immediately if you have an allergic reaction. Call 911 or go to the nearest emergency room if your symptoms are severe. Do not take this drug again if you’ve ever had an allergic reaction to it.
Combining this drug with alcohol may worsen the side effects you may observe. Modifying the drug dose without consulting a physician to amplify its impact is also not recommended. Cyclobenzaprine reduced or abolished skeletal muscle hyperactivity in several animal models. Animal studies indicate that cyclobenzaprine does not act at the neuromuscular junction or directly on skeletal muscle.
Talk to your care team about the use of this medication in children. If this medication upsets your stomach, take it with food or milk. Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
An individual might abuse Flexeril in order to feel relaxed, mildly euphoric, or sedated. Flexeril produces a variety of anticholinergic effects in high doses, altering the activity of brain neurotransmitters. Additionally, Flexeril users may experience mild withdrawal symptoms if the drug is used chronically in high doses. It is also possible for serious cyclobenzaprine side effects to occur, like seizures, heart arrhythmias, heart attack, or stroke. These are more likely to occur when a person has too much cyclobenzaprine in their system, for instance, if their prescription dose is too high or if they are misusing the drug. Sometimes, muscle relaxants like cyclobenzaprine are used “off-label” to treat conditions they’re not approved for, such as fibromyalgia.
Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body. Examples of drugs that can cause interactions with cyclobenzaprine are listed below. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
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In this study cyclobenzaprine (10mg/d) failed to significantly improve sleep in the short term but this may have been due to the relatively low dose employed. The usual dose is 5–10mg three times daily and treatment for more than 2–3 weeks is not recommended. Combining any of these drugs with alcohol or other depressants (including antihistamines, narcotics and some dental anesthetics) can make side effects more severe. Also, many of the medicines used to treat fibromyalgia work by boosting the amount of serotonin in your body. Taking two or more of these drugs together could lead to a potentially life-threatening condition called serotonin syndrome. Symptoms usually begin within hours of combining the drugs and include confusion, agitation, irregular heartbeat, unstable blood pressure, tremors, muscle rigidity, nausea and vomiting.